INTERMEDIATES

INTERMEDIATES

(S)-3-Hydroxypyrrolidine

Product 

CAS No. 

Chemical Name 

8461648-39-5

871700-24-2

22766-68-3

871700-25-3

1462-37-9

Trametinib Intermediate 

Trametinib Intermediate 

Larotrectinib Intermediate 

100243-39-8

Larotrectinib Intermediate 

1363380-51-1

5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine

(2R)-2-(2,5-difluorophenyl)pyrrolidine

1218935-59-1

Larotrectinib Intermediate 

Larotrectinib

1223403-58-4

Larotrectinib

Nilotinib Intermediate 

641571-11-1

3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

Nilotinib Intermediate 

Nilotinib Intermediate 

641569-96-2

641569-94-0

3-[(Aminoiminomethyl)amino]-4-methyl-benzoic acid ethyl ester mononitrate

4-methyl-3-[(4-pyridin-3-ylpyrimidin-2- yl)amino]benzoic acid

2,3-Dimethyl-2H-indazol-6-amine (hydrochloride)

2,3-Dimethyl-2H-indazol-6-amine

444731-72-0

Pazopanib Intermediate 

635702-60-2  

Pazopanib Intermediate 

Pazopanib Intermediate 

Pazopanib Intermediate 

444731-75-3

444731-74-2

N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6- amine

856867-55-5

Tedizolid phosphate

856866-72-3

(R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone

Trametinib Intermediate 

871700-22-0

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6- (methylamino)pyrimidine-2,4(1H,3H)-dione

N-(3-(3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8- dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido [2,3-d]pyrimidin-5-ylamino)phenyl)acetamide

Ethyl quinuclidine-4-carboxylate

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy- 6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

Diphenyl(quinuclidin-4-yl)methanol

((2-Bromoethoxy)methyl)benzene

22766-67-2

Ethyl quinuclidine-4-carboxylate (hydrochloride)

1708997-43-6

8-((3R,4S)-4-ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine hydrochloride, Upadacitinib

2095311-51-4

Benzyl(3S,4R)-3-ethyl-4-(3H-imidazo[1,2- a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidine-1- carboxylate

1869118-24-0

Ethyl(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2- yl]carbamate

29823-21-0

8-Bromooctanoic acid ethyl ester